FIG. 4.

Sre1 pathway mutants are sensitive to different chemical agents. Tenfold serial dilutions of the indicated strains were spotted on YES medium without supplement (−) or YES medium supplemented with different chemicals and incubated at 30°C for 3 days. (A) Fluc, fluconazole (250 ng/ml); Vori, voriconazole (7.5 ng/ml). (B) The CoCl₂ concentration was 0.7 mM. The pH 4 YES medium was included as control, since the YES medium was adjusted to pH 4 before NaNO₂ (1 mM final concentration) was added. The names of the genes studied are indicated on the left.