FIG. 8.
Mss11-stimulated hyphal development in C. albicans requires Flo8. (A) FLO8 overexpression suppresses the defect of mss11/mss11 mutant in filamentous growth. (B) Effect of MSS11 overexpression in the flo8/flo8 mutant. In panels A and B, the cells were induced in YPD plus 10% serum for 3.5 h at 37°C. (C) Northern analysis of HWP1 in the wild-type (CAF2-1), mss11/mss11 (CSL3), mss11/mss11 + vector (CSL4 + pBA1), mss11/mss11 + ADH1p-FLO8 (CSL4 + pBA1-FLO8), flo8/flo8 (CCF3), flo8/flo8 + vector (CCF4 + pBA1), and flo8/flo8 + ADH1p-MSS11 (CCF4 + pBA1-MSS11) strains. The experiment in panel C was carried out under the same conditions as in panels A and B.