TABLE 1.

Effect of LmAPX overexpression on cellular GSH level^a

Time (h)	Fluorescence units (mean ± SEM)b after treatment with:
	H2O2		CPT
	Control cells	LmAPX-overexpressing cells	Control cells	LmAPX-overexpressing cells
0	318 ± 12	322 ± 10	309 ± 15	312 ± 20
1	185 ± 10*	272 ± 13*	209 ± 10*	296 ± 22*
2	134 ± 8*	231 ± 11*	172 ± 12*	260 ± 15*
3	75 ± 5*	139 ± 8*	148 ± 10*	216 ± 14*
4	62 ± 4*	112 ± 7*	102 ± 4*	172 ± 8*

^aThe intracellular GSH level was measured using monochlorobimane after treatment with either CPT (5μM) or H₂O₂ (1 mM). An increase in fluorescence units reflects a larger amount of GSH present in the cells. All experiments were performed in triplicate.

^b*, P < 0.01.