TABLE 1.
Genes of the CWI pathway in different fungi
| Gene function | Gene(s) in: |
||||||
|---|---|---|---|---|---|---|---|
| S. cerevisiae | S. pombe | A. nidulans | A. fumigatus | C. albicans | C. neoformans | N. crassa | |
| Rho1-GTP form activates Pkc1 | RHO1 | rho1+ | RHOA | RHO1 | RHO1 | rho-1 | |
| Serine/threonine kinase that regulates a MAPK activation pathway | PKC1 | pck1+, pck2+ | PKCA | PKC1 | PKC1 | pkc | |
| MAPKKK | BCK1/SLK1 | mkh1+ | BCK1 | mik-1 | |||
| MAPKK | MKK1, MKK2 | pek1+/skh1+ | MKK2 | mek-1 | |||
| MAPK | SLT2/MPK1 | pmk1+/spm1+ | MPKA | MPKA | MKC1 | MPK1 | mak-1 |
| Transcription factor activated by MAPK | RLM1 | ||||||
| Transcription factor activated by MAPK made up of Swi4/Swi6 | SBF genes | ||||||