FIG. 1.

Schematic representation of the SgrA LPXTG surface protein and the EcbA MSCRAMM. Organization of the SgrA and EcbA proteins identified from the E. faecium TX0016 genome sequence as published at DDBJ/EMBL/GenBank is shown. Signal sequences are depicted by an S, a putative ligand binding domain is indicated by an A, and the Ser-Ser-Glu-Ser-Ser-Thr repeats are numbered. The cell wall sorting signal is depicted as a striped box, starting at the LPETG or FPQTG sortase substrate motif. The putative latching regions are depicted in gray, the Cna B domains are indicated by white boxes, the phenylalanine box is indicated in black, and the proline rich region is indicated by “Pro.”