TABLE 1.

Top 20 genes with the K4me3 decreasing and transcriptional downregulation in the absence of MII1

Gene	Product or other description	Expression level			ChIP-chip peak score (log2)	ChIP-qPCR fold change (log2)
		MII1−/−/MII1+/+ (log2)	P value	Adjusted P value
Thbd	Thrombomodulin	−11.10	5.70E−05	1.39E−03	−4.75	−6.18
Kctd12b	Potassium channel tetramerization domain containing 12b	−8.08	5.86E−03	2.26E−02	−3.86	−5.46
Hoxc9	Homeobox C9	−6.53	7.14E−08	3.67E−04	−4.25	−6.04
Rspo2	R-Spondin 2 homolog (Xenopus laevis)	−6.52	4.64E−07	3.67E−04	−4.10	−1.37
Mgp	Matrix Gla protein	−6.50	5.69E−06	5.00E−04	−4.09	−6.25
Bnc1	Basonuclin 1	−8.28	1.91E−04	2.61E−03	−2.10
Plek	Pleckstrin	−5.74	1.21E−06	3.67E−04	−4.41	−6.09
Tcf2	HNF1 homeobox B	−4.59	7.09E−06	5.43E−04	−5.28	−6.27
C4bp	Complement component 4 binding protein	−6.88	3.60E−07	3.67E−04	−2.99
Pax9	Paired box gene 9	−6.42	1.36E−07	3.67E−04	−3.43	−5.03
9030425E11Rik	RIKEN cDNA 9030425E11 gene	−7.63	1.18E−07	3.67E−04	−2.16
II20ra	Interleukin 20 receptor alpha	−6.57	1.01E−06	3.67E−04	−3.20	−4.78
Abi3bp	ABI gene family, member 3 (NESH) binding protein	−7.06	6.97E−03	2.56E−02	−2.56
Dkk3	Dickkopf homolog 3 (Xenopus laevis)	−5.95	4.85E−06	4.81E−04	−3.49	−5.80
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	−6.37	5.14E−06	4.85E−04	−3.01
Ebf3	Early B-cell factor 3	−5.10	5.32E−02	1.11E−01	−4.26	−5.52
Tgfbi	Transforming growth factor, beta induced	−5.85	8.74E−07	3.67E−04	−3.51	−4.27
Pitx2	Paired-like homeodomain transcription factor 2	−6.83	6.69E−03	2.49E−02	−2.23
Sfrp1	Secreted frizzled-related protein 1	−5.18	1.18E−03	7.62E−03	−3.79
Enpp3	Ectonucleotide pyrophosphatase/phosphodiesterase 3	−6.62	8.58E−03	2.96E−02	−2.30