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SOFT determination of HIV-1Ba-L growth in VQAB/IHM tissue explants. The SOFT (•) is shown for low-yield (maximum p24 level, <1,500 pg/ml) (a), medium-yield (maximum p24 level, 1,500 to 20,000 pg/ml) (b), and high-yield (maximum p24 level, >20,000 pg/ml) (c) assays. Each line represents virus growth for each of 12 donors, where each donor is distinguished by the line pattern within each panel.
