TABLE 2.
LDA of various endpoint measuresa
| Endpoint measure of virus growth | R2 | F value | Probability (F) |
|---|---|---|---|
| SOFT | 0.93 | 57.24 | <0.0001 |
| Log SOFTb | 0.96 | 140.02 | <0.0001 |
| Day 12 | 0.67 | 9.12 | 0.007 |
| Day 15 | 0.38 | 2.71 | 0.120 |
| AUC | 0.60 | 6.76 | 0.016 |
| Slope | 0.68 | 9.51 | 0.006 |
a
Results of LDA in which virus endpoint measures of viral growth (pg/ml p24) in explant tissues were differentiated between low (five assays), medium (three assays), and high (four assays).
b
Due to multicolinearity between the linear and logarithmic SOFT results, the log10 p24 at the SOFT (log SOFT) was entered into a separate LDA.