TABLE 1.

Concordance between phenotype (MIC determined by Etest) and genotype (sequencing or real-time PCR) for H. pylori strains included in the study

H. pyloria	n	rrl genotype			gyrA genotype
		Wild type	Missense mutation	No data	Wild type	Missense mutation	No data
Phase 1
Development panel H. pylori strains	126
CLA-R	40	3b	37
CLA-S	86	86	0
FQ-R	21				0	21
FQ-S	105				105c	0
Phase 2
Clinical H. pylori strains	92
CLA-R	48	2	34	12
CLA-S	44	21	1	22
FQ-R	41						41
FQ-S	51						51
Gastric biopsy specimens	105
CLA-R	49	0	49
CLA-S	56	56	10
FQ-R	26						26
FQ-S	79						79

^aCLA, clarithromycin; FQ, fluoroquinolone; S, susceptible; R, resistant.

^bClarithromycin MIC, 2 μg/ml.

^cSixteen strains harbored a Thr87, which confers fluoroquinolone susceptibility.