TABLE 4.
Genotype | No. in clinical strains (n = 92) | No. in biopsy specimens (n = 105) |
---|---|---|
23S rRNA gene (rrl) | ||
WT | 48 | 57 |
MUT1 | 6 | 5 |
MUT3 | 25 | 34 |
WT + MUT1 | 2 | 1 |
WT + MUT3 | 5 | 5 |
WT + MUT1 + MUT3 | 1 | 0 |
WT + MUT1 + MUT2 | 0 | 1 |
WT + MUT2 + MUT3 | 1 | 1 |
MUT1 + MUT3 | 3 | 1 |
gyrA gene | ||
Codon 87 | ||
WT1 | 34 | 41 |
WT2 | 8 | 11 |
WT3 | 15 | 8 |
WT4 | 2 | 6 |
WT1+WT2 | 15 | 20 |
WT2+WT4 | 1 | 0 |
WT3+WT4 | 0 | 2 |
WT1+WT2 + WT3 | 0 | 1 |
WT 1 + MUT | 2 | 3 |
MUT | 7 | 2 |
WT1+WT2 + MUT | 1 | 0 |
No WT or MUT band | 7 | 11 |
Codon 91 | ||
WT | 73 | 93 |
MUT1 | 6 | 5 |
MUT2 | 4 | 3 |
MUT3 | 1 | 1 |
WT + MUT1 | 4 | 0 |
WT + MUT3 | 1 | 0 |
WT + MUT2 | 2 | 1 |
WT + MUT1 + MUT2 | 1 | 0 |
WT + MUT1 + MUT3 | 0 | 1 |
No WT or MUT band | 0 | 1 |
WT, wild-type allele; MUT, mutated allele (see Table 2 for the codon sequences).