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Haploview LD plot of GRIK1 3’region markers: LD plot from Haploview 3.32 for EA subjects (507 control subjects and 1057 subjects with AD). Pairwise SNP |D’| values (x100) of linkage are shown together with 2 haplotype blocks identified using the four-gamete rule. Darkened blocks indicate SNP pairs without evidence of extensive recombination (i.e. 4-gamete rule for haplotype block characterization with at least one 2-SNP haplotype having a frequency < 0.02).
