TABLE 2.
Clonal analysis of four virus populations containing mixtures at positions 155 and 148 confirmed that these mutations occurred on separate virions
| Subject no. | Virus (no. of clones) | Mutation(s)a |
|||
|---|---|---|---|---|---|
| E92 | N155 | G140 | Q148 | ||
| 3 | Population | E | N/H | G/S | Q/H |
| Clone (23) | E | H | G | Q | |
| Clone (7) | E | N | S | H | |
| 4 | Population | E | N/H | G | Q/R |
| Clone (15) | E | N | G | Q | |
| Clone (11) | E | H | G | Q | |
| Clone (3) | E | N | G | R | |
| 7 | Population | E/Q | N/H | G/A | Q/R |
| Clone (20) | Q | H | G | Q | |
| Clone (9) | E | N | A | R | |
| 10 | Population | E/Q | N/H | G | Q/K |
| Clone (2) | Q | N | G | Q | |
| Clone (13) | Q | H | G | Q | |
| Clone (3) | E | H | G | Q | |
| Clone (5) | E | N | G | K | |
a
Bold font indicates RAL resistance mutation.