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Intrahost variability of HVR495 and HVR575. Amino acids within HVR1, HVR495, and HVR575 are derived from 18 to 25 clones after E2 sequencing in three representative patients: patient 129, subtype 3a; patient 299, subtype 3a; and patient 396, subtype 1a. The consensus sequence is given in the top line. A dot indicates that the amino acid within a single clone is identical to the consensus amino acid.
