Differential viral-RNA rescue effects of BFA-resistant GBF1 mutants M832L and A795E in HeLa cells. RNA replication of wt and mutant replicons of PV (A, C, and E) or CVB3 (B, D, and F) in the presence or absence of BFA in nontransfected (control) cells (A and B), in cells transiently transfected with GBF1 M832L (C and D), or in cells transiently transfected with GBF1 A795E. RNA replication was measured by determining the amount of Renilla luciferase production.