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. 2009 Sep 9;83(22):11581–11587. doi: 10.1128/JVI.01490-09

FIG. 2.

FIG. 2.

HRV1a infection does not induce IRF-3 homodimers. HeLa cells were infected with either SeV or HRV1a and harvested at the times indicated. Cell extracts were prepared and fractionated by native PAGE, and IRF-3 was detected by Western blot analysis using polyclonal rabbit antiserum against IRF-3, which strongly recognizes both the monomeric and dimeric forms of the protein. Monomeric and dimeric forms of IRF-3 are labeled. p.i., postinfection.