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. 2009 Aug 26;83(21):11407–11411. doi: 10.1128/JVI.01211-09

FIG. 1.

FIG. 1.

Elevated CD38 levels in CD4 and CD8 T cells in HCV/HIV-1-coinfected subjects despite effective HAART. (A) Representative dot plots of CD38 staining in CD8 T cells. (B) CD38 expression in CD8 T cells in coinfected patients (n = 14) in comparison to HCV (n = 11)- and HIV-1 (n = 9)-monoinfected subjects as well as to healthy donors (n = 21). (C) CD38 expression in CD4 T cells in the four study groups. (D) Spearman rank correlation between the CD38 expression in CD4 and CD8 T cells in coinfected subjects. CD38 expression in CD8 T cells (E) and CD4 T cells (F) in coinfected patients with HCV genotype 1 (Gt1) (n = 10) infection and HCV genotype 2 or 3 (Gt2/3) infection (n = 4) and healthy donors (n = 21). Means and standard errors are shown. Statistical analysis performed was one-way analysis of variance on ranks followed by Dunn's multiple comparison test. *, P < 0.05; **, P < 0.01; ***, P < 0.001. All statistical analyses were performed using GraphPad Prism software 5.0 (GraphPad Software, Inc., San Diego, CA).