TABLE 1.
Subject characteristics at baseline
| Characteristic | Value for groupa |
|||
|---|---|---|---|---|
| HCV/HIV-1 coinfected | HCV monoinfected | HIV monoinfected | Healthy control | |
| Subjects (n) | 14 | 11 | 9 | 21 |
| Sex [no. of patients (%)] | ||||
| Female | 3 (21) | 5 (50) | 2 (22) | 9 (43) |
| Male | 11 (79) | 6 (50) | 7 (78) | 12 (57) |
| Age (yr) (range) | 43 (21-53) | 52 (43-59) | 46 (29-67) | 45 (32-59) |
| CD4 absolute median (cells/μl) (range) | 499 (250-1370) | 729 (200-1746) | 605 (370-720) | 845 (441-1491) |
| CD4 median % (range) | 27 (12-45) | 44 (38-57) | 30 (21-41) | 46 (31-67) |
| CD8 absolute median (cells/μl) (range) | 910 (530-2440) | 666 (352-754) | 770 (520-1770) | 443 (195-776) |
| CD8 median % (range) | 50 (24-70) | 26 (15-39) | 46 (24-64) | NA |
| HIV ART [no. of patients (%)] | 14 (100) | NA | 9 (100) | NA |
| HIV load median (copies/ml) (range) | <50 (<50) | NA | <50 (<50) | NA |
| HCV genotype [no. of patients (%)] | ||||
| 1 | 10 (72) | 2 (18) | NA | NA |
| 2 | 2 (14) | 4 (36) | NA | NA |
| 3 | 2 (14) | 5 (46) | NA | NA |
| Serum HCV RNA median (IU/ml) (range) | 3.64 × 106 (0.068 × 106−20.0 × 106) | 0.57 × 106 (0.023 × 106-3.65 × 106) | NA | NA |
a
NA, not applicable.