FIG. 2.

Multiple sequence alignment for early proximal part of the NCCR. CLUSTAL multiple sequence alignment was performed for JCV, BKV, and SV40 using the GenBank entries specified in the legend to Fig. 1. Sequences in red are shared for all three viruses and are also indicated with an asterisk. Sequences shared between JCV and BKV are in blue. Nonmatching sequences are in green. The underlined CAT corresponds to the opposite-strand ATG start codon for the early genes. Experimentally verified binding sites are shown for NF-κB (single underline) and C/EBPβ (double underline). Numbering is relative to the Mad-1 strain of JCV (GenBank accession no. NC_001699).