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. Author manuscript; available in PMC: 2010 Mar 4.
Published in final edited form as: Cell. 2009 Sep 4;138(5):1005–1018. doi: 10.1016/j.cell.2009.06.023

Figure 2. Loss of function in cebp-1 suppresses rpm-1(lf).

Figure 2

(A) CEBP-1 contains a bZip domain most similar to those of C/EBP proteins. (B) cebp-1(lf) suppresses motor neuron presynaptic morphology defects of rpm-1 cell-autonomously (juIs1 marker). Right panel, quantification of SNB-1::GFP puncta (n ≥ 10 animals per genotype; data shown as mean ± SEM). (C) cebp-1(lf) suppresses the touch axon overextension of rpm-1 cell-autonomously (muIs32 marker). (D) The bZip domain is required for cebp-1 function. (E) CEBP-1(R290C) and CEBP-1(S289L) have dominant-negative activity. (B–E) Unless noted, alleles are rpm-1(ju44) and cebp-1(ju659). Quantitation, labels, details of mutant phenotypes, promoters and statistics as in Figure 1. Scales, 10 μm.