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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Neurobiol Learn Mem. 2009 May 10;92(3):455–459. doi: 10.1016/j.nlm.2009.05.001

Fig. 1.

Fig. 1

Age-dependent impairments of contextual fear conditioning in 5XFAD mice. (A–C) 5XFAD mice at 3–4 months (A), 6–7 months (B) and 10–15 months (C) of ages, and their respective wild-type littermate mice were trained with 2 CS/US pairings for contextual fear conditioning. 5XFAD mice at 6–7 and 10–15 months of age but not at 3–4 months of age show significantly lower levels of contextual freezing than wild-type controls when tested 24 h after training (n = 15–21 mice per group). * p < 0.05 versus wild-type controls. All data are presented as mean ± SEM.