Table 1.
Genes Scoring With Four siRNAs
| Category | Symbol | Comments |
|---|---|---|
| Apoptosis | BIRC5 | Baculoviral IAP repeat-containing 5 |
| CASP8AP2 | CASP8 associated protein 2 | |
| Cell Cycle | CDCA5 | Cell division cycle associated 5 |
| CENPE | Centromere protein E | |
| STK6 | Aurora kinase A | |
| Channel | SLC28A2 | Solute carrier family 28 |
| LRP1B | Low density lipoprotein-related protein 1B | |
| Cytoskeletal-Related | CKAP5 | Cytoskeleton associated protein 5 |
| KRTAP12-3 | Keratin associated protein 12-3 | |
| KIF11 | Kinesin family member 11 | |
| DNA Binding | SON | SON DNA binding protein |
| PABPC4 | Poly(A) binding protein, cytoplasmic 4 | |
| DNA replication/repair | ERCC6 | Excision repair cross-complementation group 6 |
| XAB2 | XPA binding protein 2 | |
| DBF4/ASK | DBF4 homolog; activator of S phase kinase | |
| CHEK1/CHK1 | Checkpoint kinase 1 homolog | |
| CLSPN | Claspin homolog | |
| MCM10 | Minichromosome maintenance complex protein 10 | |
| RPA1 | Replication protein A1, 70kDa | |
| RPA2 | Replication protein A2, 32kDa | |
| RRM1 | Ribonucleotide reductase M1 polypeptide | |
| RRM2 | Ribonucleotide reductase M2 polypeptide | |
| SETD8/SET8 | SET domain containing 8 | |
| TIMELESS | Timeless homolog | |
| Other | COPZ1 | Coatomer protein complex, subunit zeta 1 |
| CSA2 | Cytokine, down-regulator of HLA II | |
| ITGB1 | Integrin, beta 1 | |
| BRD8 | Bromodomain containing 8 | |
| NCAN/CSPG3 | Neurocan | |
| FAM24A | Familywith sequence similarity 24, member A | |
| FKBP6 | FK506 binding protein 6 | |
| PSMD3 | Proteasome 26S non-ATPase subunit 3 | |
| Polymerase | POLR2G | Polymerase (RNA) II (DNA-directed) polypeptide G |
| POLR2I | Polymerase (RNA) II (DNA-directed) polypeptide I | |
| RNA Splicing | PRPF19/PRP19 | PRP19/PSO4 pre-mRNA processing factor 19 homolog |
| CRNKL1 | Crooked neck pre-mRNA splicing factor-like 1 | |
| HNRPC | Heterogeneous nuclear ribonucleoprotein C | |
| CWC22/KIAA1604 | CWC22 spliceosome-associated protein homolog | |
| LSM2 | LSM2 homolog, U6 small nuclear RNA-associated | |
| PRPF8 | PRP8 pre-mRNA processing factor 8 homolog | |
| SART1 | Squamous cell carcinoma antigen recognized by T cells | |
| SF3A1 | Splicing factor 3a, subunit 1 | |
| SF3A2 | Splicing factor 3a, subunit 2 | |
| SF3B2 | Splicing factor 3b, subunit 2 | |
| SF3B4 | Splicing factor 3b, subunit 4 | |
| SKIIP | SNW domain containing 1; SKI-interacting protein | |
| SNRPA1 | Small nuclear ribonucleoprotein polypeptide A1 | |
| SNRPB | Small nuclear ribonucleoprotein polypeptides B and B1 | |
| SNRPD1 | Small nuclear ribonucleoprotein D1 polypeptide | |
| SNRPD3 | Small nuclear ribonucleoprotein D3 polypeptide | |
| WBP11 | WW domain binding protein 11 | |
| AQR | Aquarius homolog | |
| CDC40 | Cell division cycle 40 homolog | |
| CDC5L | CDC5 cell division cycle 5-like | |
| Transcription Factor | ZNF157 | Zinc finger protein 157 |
| ZNF16 | Zinc finger protein 16 |