Table 1.

Arthritis-linked loci in (DA × LEW.1AV1)F₂ progeny

Chromosome/marker	Distance, cM	P values			Disease genotype
		Susceptibility	Incidence	Severity
2/D2Mit15		4 × 10−2	2 × 10−2	4 × 10−2	LL
4/D4Mit12	28.0	2 × 10−2	NS	1 × 10−2	DD
4/D4Mgh10		4 × 10−13	9 × 10−11	1 × 10−4	DD
6/D6Mgh7	35.4	2 × 10−2	NS	NS	DL
6/D6Mit1		3 × 10−2	NS	NS	DD
8/D8Mgh1		8 × 10−3	2 × 10−2	NS	DD
10/D10Mgh1		2 × 10−6	2 × 10−4	8 × 10−3	DD
14/D1BR		NS	NS	3 × 10−2	DD
19/D19Mgh1		NS	NS	1 × 10−2	DD

Chromosome regions linked to disease with P < 0.05 and the marker with the lowest P value are presented for each region. NS, nonsignificant; cM, centimorgan(s). Susceptibility* is the maximum arthritis score of all animals (0–92) in relation to genotypes (DD = DA homozygous, LL = LEW.1AV1 homozygous, and DL = heterozygous) analyzed by the nonparametric Kruskall–Wallis test (2 df). Incidence is all animals divided into the categories affected (scores > 0) or unaffected (score = 0) in relation to genotypes and analyzed by χ² test. 

^*Severity denotes arthritis severity in affected animals only (scores > 0) in relation to genotypes analyzed by the Kruskall–Wallis test (2 df).