Table 2.

Two arthritis-linked loci in (DA × LEW.1AV1)F₂ progeny with genome-wide significance for linkage

Chromosome	Marker	Gene	Distance, cM	P values
4	D4Mit24	NPY		3 × 10−2
			9.4
4	D4Mit12	Fabp1		2 × 10−2
			6.2
4	D4Mgh17	Spr		1 × 10−4
			14.4
4	D4Mgh7			4 × 10−6
			12.9
4	D4Mgh10			4 × 10−13
			0.8
4	D4Mit21			3 × 10−13
			0.3
4	EN3C	Eno2		5 × 10−13
			8.0
4	D4Mit27			1 × 10−7
			7.8
4	D4Mgh21			2 × 10−6
10	D10Mit13			2 × 10−3
			3.9
10	IGFBP4	lgfbp4		2 × 10−3
			6.3
10	BAND3A	Band3A		2 × 10−5
			4.8
10	D11Mit58*			1 × 10−4
			21.3
10	D10Mgh1			2 × 10−6

Arthritis susceptibility (all F₂ rats with scores of 0–92, Fig. 1) in relation to genotypes (DD, DL, or LL) at different locations (markers) were calculated with the nonparametric Kruskall–Wallis test. Distances between consecutive markers were calculated by mapmaker. 

^*A mouse marker.