Table 1.
Experimental animal number: treatment distribution
| Analysis | Treatment | Postfracture | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 Days | 10 Days | 21 Days | 28 Days | 42 Days | |||||||
| Placebo | Pred | Placebo | Pred | Placebo | Pred | Placebo | Pred | Placebo | Pred | ||
| Radiography | No OP-1 or collagen | 6 | 6 | 6 | 6 | 6 | 5 | ||||
| OP-1 and collagen | 6 | 7 | 6 | 6 | 6 | 6 | |||||
| Collagen only | 6 | 5 | |||||||||
| Histomorphometry | No OP-1 or collagen | 6 | 5 | 6 | 6 | 6 | 6 | 6 | 6 | 5 | 5 |
| OP-1 and collagen | 6 | 6 | 6 | 7 | 4 | 5 | 6 | 6 | 6 | 4 | |
| Collagen only | 6 | 5 | |||||||||
| Mechanics | No OP-1 or collagen | 7 | 6 | ||||||||
| OP-1 and collagen | 6 | 5 | 6 | 6 | |||||||
| Collagen only | 5 | 6 | |||||||||
Pred = 2.2 mg/kg prednisolone slow-release subcutaneously; OP-1 = osteogenic protein 1.