Table 2.
Odds ratios (95% confidence intervals) for incidence of psychotic disorders in relation to prenatal and perinatal characteristics. Values derived from conditional logistic regression model
Schizophrenia (n=163) | Affective psychosis (n=193) | Reactive psychosis (n=281) | |
---|---|---|---|
Maternal factors | |||
Age at delivery (years): | |||
⩽19 | 0.8 (0.4 to 1.7) | 1.0 (0.5 to 2.0) | 1.3 (0.8 to 2.2) |
20-29* | 1.0 | 1.0 | 1.0 |
⩾30 | 1.2 (0.8 to 1.8) | 1.4 (0.9 to 2.0) | 1.3 (0.9 to 1.8) |
Parity: | |||
1 | 1.3 (0.9 to 1.9) | 1.0 (0.7 to 1.4) | 1.1 (0.9 to 1.5) |
2-3* | 1.0 | 1.0 | 1.0 |
4 | 2.0 (1.0 to 3.8)† | 1.0 (0.5 to 2.2) | 2.1 (1.3 to 3.5) |
Pregnancy and delivery factors | |||
Hypertensive diseases | 1.3 (0.6 to 3.1) | 1.6 (0.7 to 3.5) | 0.8 (0.4 to 1.7) |
Diabetes | 7.8 (0.9 to 67.6) | 0.7 (0.1 to 6.8) | 3.4 (0.5 to 21.5) |
Bleeding during pregnancy | 3.5 (1.2 to 10.3) | 1.1 (0.4 to 2.9) | 1.2 (0.5 to 3.0) |
Uterine atony | 1.4 (0.7 to 2.6) | 2.2 (1.2 to 4.1) | 1.0 (0.6 to 1.8) |
Child characteristics | |||
Birth weight for gestational age: | |||
Small (⩾2 SD below mean) | 1.5 (0.7 to 3.1)† | 1.3 (0.7 to 2.7) | 1.0 (0.6 to 1.7) |
Mean* | 1.0 | 1.0 | 1.0 |
Large (⩾2 SD above mean) | 0.5 (0.2 to 1.6) | 1.2 (0.5 to 2.9) | 0.9 (0.4 to 2.0)† |
Ponderal index (centiles)‡: | |||
⩽5 | 2.1 (0.8 to 4.3) | 0.6 (0.3 to 1.4) | 1.1 (0.6 to 2.0) |
6-94* | 1.0 | 1.0 | 1.0 |
⩾95 | 1.0 (0.4 to 2.2) | 1.0 (0.5 to 2.2) | 1.4 (0.8 to 2.5) |
Apgar score at 1 minute: | |||
0-6 | 0.97 (0.4 to 2.3) | 1.3 (0.6 to 2.7) | 1.8 (0.9 to 3.7) |
7-10* | 1.0 | 1.0 | 1.0 |
Asphyxia | 1.0 (0.6 to 1.8) | 1.4 (0.9 to 2.3) | 0.8 (0.5 to 1.3) |
Season of birth | |||
January-April | 1.4 (1.0 to 2.0) | 1.5 (1.1 to 2.0) | 1.2 (0.9 to 1.5) |
May-December* | 1.0 | 1.0 | 1.0 |
Reference category.
Significant interaction with sex (P<0.05).
(100×(birth weight (g))/(birth length (cm))3. Entered in a separate model in place of birth weight for gestational age.