Table 4. Genes with ≥2-fold reduced expression in diabetic diaphragm assigned to over-represented gene ontology groups.

Gene Name	Gene Symbol	GeneID	Fold Change
Carbohydrate and Alcohol Metabolism
neuraminidase 2	Neu2	29204	−8.5
phosphofructokinase, liver, B-type	Pfkl	25741	−3.7
solute carrier family 37 (glycerol-6-phosphate transporter), member 4	Slc37a4	29573	−2.5
glycerol-3-phosphate dehydrogenase 2	Gpd2	25062	−2.3
amylase 1, salivary	Amy1	24203	−2.3
phosphoglycerate mutase 2	Pgam2	24959	−2.1
lactate dehydrogenase A	Ldha	24533	−2.0
phosphoglucomutase 1	Pgm1	24645	−2.0
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	Dlat	81654	−2.0
Extracellular Matrix and Collagen
collagen, type III, alpha 1	Col3a1	84032	−3.7
collagen, type 1, alpha 1	Col1a1	29393	−3.5
procollagen, type I, alpha 2	Col1a2	84352	−3.2
fibrillin 1	Fbn1	83727	−2.8
secreted acidic cysteine rich glycoprotein	Sparc	24791	−2.7
collagen, type V, alpha 1	Col5a1	85490	−2.4
collagen, type V, alpha 3	Col5a3	60379	−2.2
Organogenesis and Organ Development
collagen, type III, alpha 1	Col3a1	84032	−3.7
Parvalbumin	Pvalb	25269	−3.1
acyl-CoA synthetase long-chain family member 6	Acsl6	117243	−2.7
ret proto-oncogene	Ret	24716	−2.5
chemokine (C-X-C motif) ligand 12	Cxcl12	24772	−2.4
reticulon 4	Rtn4	83765	−2.4
dimethylarginine dimethylaminohydrolase 1	Ddah1	64157	−2.1