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. 2009 Nov 17;4(11):e7789. doi: 10.1371/journal.pone.0007789

Table 2. LRT tests for HA1 sequences of human A(H1N1) influenza viruses.

LRT (M2a − M1a) (2Δl) (p-values)1 LRT (M8 − M7) (2Δl) (p-values)1 LRT (M8 − M8a) (2Δl) (p-values)2
I-i 1918∼1919 (5 strains) 3.44 (0.1791) 3.46 (0.1773) 3.44 (0.0318)
I-ii 1979∼2000 (45 strains) 0 0 0
I-iii 2000∼2001 (22 strains) 2.98 (0.2254) 2.84 (0.2417) 2.96 (0.0427)
I-iv 2001∼2007 (89 strains) 1.86 (0.3946) 0.34 (0.8437) 1.16 (0.1407)
I-v 2006∼2008 (100 strains) 62.42 (0.0000) 65.32 (0.0000) 61.70 (0.0000)
II 2007∼2009 (74 strains) 0.78 (0.6771) 0.80 (0.6703) 2.44 (0.0591)
1

We used the degree of freedom of 2 for these LRT tests that is expected to be too conservative. 2 The p-values were calculated from χ2 distribution using degree of freedom of 1 that was then divided by a factor of 2 for the mixture distribution, as suggested by the author of PAML 4.0.