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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2009 May 15;47(3):312–320. doi: 10.1016/j.freeradbiomed.2009.05.012

Figure 7. Effect of Gpx4 on CL peroxidation.

Figure 7

Tg(GPX4+/0) and Gpx4+/− mice and their corresponding Wt littermates were either untreated or treated with diquat and CL peroxidation determined by measuring mitochondrial bound NAO as described in the Experimental Procedures. Panel A: Quantification of CL peroxidation in Tg(GPX4+/0) mice (solid bars) and their Wt littermates (open bars). Panel B: Quantification of CL peroxidation in Gpx4+/− mice (shaded bars) and their Wt littermates (hatched bars). All values are mean ± SEM of data obtained from 4 mice. The asterisks indicate the differences that are significantly different.