Table 3.
Multivariate models of the likelihood of taking medications among the 578 patients with Mild Cognitive Impairment (MCI).
| Characteristic | Anti-AD* Medications | Statins | Antioxidants | Folic Acid |
|---|---|---|---|---|
| Odds Ratio (95% Confidence Interval) | ||||
| Age | 1.26 (1.01 – 1.57) | --- | --- | --- |
| Education | 1.39 (1.06 – 1.82) | --- | 1.42 (1.07 – 1.89) | 1.34 (0.83 – 2.16) |
| Non-White Race | --- | --- | --- | 2.32 (1.01 – 5.31) |
| Male | 1.26 (0.84 – 1.89) | 1.58 (1.10- 2.27) | --- | 2.84 (1.26 – 6.42) |
| MMSE* | 0.87 (0.70 – 1.09) | --- | --- | --- |
| Diabetes | --- | 2.40 (1.52 – 3.80) | 0.53 (0.29 – 0.98) | --- |
| Hypertension | --- | 2.19 (1.48 – 3.24) | --- | --- |
| Myocardial Infarct | --- | 4.34 (2.03 – 9.26) | --- | --- |
| Stroke/TIA* | --- | 1.25 (0.73 – 2.12) | --- | 0.31 (0.07 – 1.37) |
| BRDRS* | 1.76 (1.38 – 2.24) | --- | --- | 1.72 (1.27 – 2.34) |
| Site | 1.00 (0.93 – 1.09) | 0.95 (0.89 – 1.02) | 1.13 (1.04 – 1.22) | 1.04 (0.91 – 1.20) |
| Amnestic Disorder | 1.83 (1.18 – 2.85) | 1.08 (0.70 – 1.67) | --- | 0.68 (0.26 – 1.75) |
| Mild Neurocognitive Disorder |
--- | 0.61 (0.40 – 0.91) | 0.75 (0.46 – 1.24) | --- |
| MCI*- Petersen or ADCS Criteria |
0.65 (0.42 – 1.00) | --- | 1.01 (0.62 – 1.63) | --- |
*
AD = Alzheimer's Disease; MMSE = Mini Mental Status Examination (range = 0 – 30 where lower score indicates poorer performance); TIA = transient ischemic attack; BRDRS = Blessed-Roth Dementia Rating Scale (range = 0 – 17 where higher score indicates poorer performance)