Figure 3.
Specificity of oxazine release from the nanoparticle platform. a, Fluorescence response of the ROS/RNS sensor following incubation with a panel of biologically relevant oxidants. b, Linear dependence of oxazine release with increasing HOCl concentrations. c, Effect of chloride ions on activation of the ROS/RNS probe and release of oxazine. Reactions were performed in the presence of MPO (11nM) and H2O2 (3.2µM).