Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Subcellular localization of phosphomimetic VASP mutants in MVD7 cells
| VASP mutant | Lamellipodia | Focal adhesions |
|---|---|---|
| AAA | o | o |
| DAA | o | + |
| ADA | o | o |
| DDA | + | + |
| AAE | o | o |
| DAE | + | + |
| ADE | – | – |
| DDE | + | o |
In MVD7 cells, subcellular localization of transiently expressed VASP mutants at lamellipodia or focal adhesions was scored as weak (–), moderate (o), or strong (+). Per mutant, 40 randomly selected cells with comparable VASP expression levels were analyzed.
