Table 2.
Five-Year Ipsilateral Breast Event Rates for Eligible Patients
| Variable | Low/Intermediate Grade |
High Grade |
||||
|---|---|---|---|---|---|---|
| No. | 5-Year Rate (%) | 95% CI | No. | 5-Year Rate (%) | 95% CI | |
| Age, years | ||||||
| < 45 | 49 | 8.5 | 0.5 to 16.5 | 11 | 54.4 | 25.1 to 84.0 |
| ≥ 45 | 509 | 5.9 | 3.8 to 8.0 | 92 | 10.3 | 3.9 to 16.7 |
| Margin size, mm | ||||||
| < 10 | 284 | 5.6 | 2.8 to 8.3 | 48 | 14.8 | 4.7 to 24.9 |
| ≥ 10 | 274 | 6.7 | 3.6 to 9.7 | 55 | 15.9 | 5.7 to 26.1 |
| Lesion size, mm | ||||||
| < 10 | 426 | 5.5 | 3.3 to 7.8 | 90 | 12.7 | 5.7 to 20.0 |
| ≥ 10* | 132 | 8.1 | 3.3 to 12.9 | 13 | 32.9 | 6.4 to 59.3 |
| Intent to use tamoxifen | ||||||
| Yes | 175 | 7.5 | 3.4 to 11.6 | 29 | 16.6 | 1.1 to 32.0 |
| No† | 383 | 5.5 | 3.1 to 7.8 | 74 | 15.3 | 7.0 to 23.7 |
| Prior tamoxifen use | ||||||
| Yes | 67 | 1.5 | 0 to 4.4 | 11 | ‡ | |
| No | 488 | 6.8 | 4.5 to 9.1 | 92 | 17.1 | 9.2 to 25.0 |
*
Tumor measured as exactly 10-mm for high grade stratum.
†
Includes those cases entered before the 2000 addendum allowing tamoxifen use.
‡
No events observed by 5 years.