Table 1.
Site of Lesion | Patient ID | MIBG Pretherapy | PET Pretherapy | Con Pretherapy | MIBG Post-Therapy | PET Post-Therapy | Con Post-Therapy | MIBG Total | PET Total | Con Total |
---|---|---|---|---|---|---|---|---|---|---|
Bone | 5 | 5 | 3 | 0.60 | 3 | 0 | 0 | 8 | 3 | 0.38 |
6 | 2 | 0 | 0 | — | — | — | 2 | 0 | 0 | |
7 | 7 | 6 | 0.86 | 4 | 3 | 0.75 | 11 | 9 | 0.82 | |
8 | 12 | 9 | 0.75 | 9 | 7 | 0.45 | 21 | 16 | 0.61 | |
9 | 4 | 1 | 0.25 | 1 | 0 | 0 | 5 | 1 | 0.20 | |
10 | 4 | 8 | 0.50 | — | — | — | 4 | 8 | 0.50 | |
11 | 1 | 1 | 1 | 2 | 1 | 0.50 | 3 | 2 | 0.67 | |
12 | 4 | 0 | 0 | 0 | 0 | — | 4 | 0 | 0 | |
13 | 10 | 8 | 0.80 | 8 | 4 | 0.50 | 18 | 12 | 0.67 | |
14 | — | — | — | 8 | 0 | 0 | 8 | 0 | 0 | |
15 | 10 | 0 | 0 | — | — | — | 10 | 0 | 0 | |
16 | 4 | 1 | 0 | 9 | 0 | 0 | 13 | 1 | 0 | |
19 | 8 | 1 | 0.13 | 0 | 0 | — | 8 | 1 | 0.13 | |
Total lesions | 71 | 38 | 33/76 | 44 | 15 | 13/46 | 115 | 53 | 46/122 | |
43.4% | 28.3% | 37.7% | ||||||||
Soft tissue | 4 | 2 | 1 | 0.50 | — | — | — | 2 | 1 | 0.50 |
8 | 1 | 3 | 0.33 | 2 | 1 | 0.50 | 3 | 4 | 0.40 | |
9 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | |
10 | 1 | 3 | 0.33 | — | 0 | — | 1 | 3 | 0.33 | |
11 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 2 | 0.50 | |
16 | 1 | 2 | 0.50 | 1 | 1 | 1 | 2 | 3 | 0.67 | |
Total lesions | 6 | 11 | 5/12 | 5 | 4 | 4/5 | 11 | 15 | 9/17 | |
41.7% | 80% | 52.9% | ||||||||
All lesions | 4 | 2 | 1 | 0.50 | — | — | — | 2 | 1 | 0.50 |
5 | 5 | 3 | 0.60 | 3 | 0 | 0 | 8 | 3 | 0.38 | |
6 | 2 | 0 | 0 | — | — | — | 2 | 0 | 0 | |
7 | 7 | 6 | 0.86 | 4 | 3 | 0.75 | 11 | 9 | 0.82 | |
8 | 13 | 12 | 0.67 | 11 | 8 | 0.46 | 24 | 20 | 0.57 | |
9 | 5 | 2 | 0.40 | 2 | 1 | 0.50 | 7 | 3 | 0.43 | |
10 | 5 | 11 | 0.45 | — | — | — | 5 | 11 | 0.45 | |
11 | 1 | 2 | 0.50 | 3 | 2 | 0.67 | 4 | 4 | 0.60 | |
12 | 4 | 0 | 0 | 0 | 0 | — | 4 | 0 | 0 | |
13 | 10 | 8 | 0.80 | 8 | 4 | 0.50 | 18 | 12 | 0.67 | |
14 | — | — | — | 8 | 0 | 0 | 8 | 0 | 0 | |
15 | 10 | 0 | 0 | — | — | — | 10 | 0 | 0 | |
16 | 5 | 3 | 0.14 | 10 | 1 | 0.10 | 15 | 4 | 0.12 | |
19 | 8 | 1 | 0.13 | 0 | 0 | — | 8 | 1 | 0.13 | |
Total lesions | 77 | 49 | 38/88 | 49 | 19 | 17/51 | 126 | 68 | 55/139 | |
43.2% | 33.3% | 39.6% |
NOTE. Only patients with bone or soft tissue lesions are included in that respective section of the table. Total lesions indicates the number of distinct anatomical lesions seen by a single modality or by the combined modalities.
Abbreviations: MIBG, metaiodobenzylguanidine; FDG-PET, [18F]fluorodeoxyglucose positron emission tomography; Con, concordance, which indicates the fraction of anatomically distinct lesions identified on both types of scan.