Table 3.

Time to Hematopoietic Recovery and Incidence of WHO Grade 3 to Grade 4 Main Adverse Events After Induction and Consolidation Treatments

Time to Recover/Adverse Event	Treatment Arm
	DNR	MXR	IDA
Time to neutrophil count > 0.5 × 109/L, days*
First induction	26	27	26
Consolidation†	22	26	26
Time to platelet count > 20 × 109/L, days*
First induction	24	25	24
Consolidation‡	20	26	26
Grade 3 or 4 infections, %
First induction	29.8	33.2	32.8
Consolidation§	13.6	24.3	22.3
Grade 3 or 4 adverse effects other than infections, %
First induction	44.5	45.9	46.0
Consolidation‖	16.8	20.4	24.0

Abbreviations: DNR, daunorubicin; MXR, mitoxantrone; IDA, idarubicin.

^*Recovery times of patients who achieved a complete remission. Results are presented as median.

^†P value, overall comparison: < .001.

^‡P value, overall comparison: < .001.

^§P value, overall comparison: .001 (MXR v DNR, P < .001; IDA v DNR, P = .001).

^‖P value, overall comparison: .008 (MXR v DNR, P = .20; IDA v DNR, P = .01).