Table 5.

Responses

Best Response	Cohort 1 (n = 27)			All Patients (N = 71)
	Response		Response Duration (months)	Response		Response Duration (months)
	No.	%		No.	%
CR	3	11	6, 14*, 63†	4	7	6, 14*, 26‡, 63†
PR	8	30	2§, 2, 5, 10, 14, 20§, 32, 76‡	20	26	1, 1, 2, 2, 2, 2§, 3, 4‡, 5, 5, 6‖, 7§, 10, 11‡, 14, 14, 15, 20§, 32, 76‡
SD	10	37	3, 3, 4, 4, 4, 6, 6, 7, 7, 8	26	38	3, 3, 3, 3, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4‖, 5, 6, 6, 6, 6, 6, 7, 7, 8, 8, 10, 11
PD	3	11		15	17
NE	3	11		6	12

Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NE, not evaluable.

^*After 14 months in CR, this patient developed several small plaques but did not require additional therapy for over 43 months.

^†Patient completed therapy 58 months prior to cut off date for this report.

^‡Patients with continued responses to therapy at time of this report.

^§Patient self-withdrew from study.

^‖Death on study.