Skip to main content
. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Nat Cell Biol. 2009 Oct 18;11(11):1287–1296. doi: 10.1038/ncb1973

Figure 2. TGFβ signalling in MTLn3E cells.

Figure 2

A: Assay showing changes in CAGA12-luciferase reporter activity in MTLn3E cells in response to 2ng/ml TGFβ1 +/−10μM SB431542 (an inhibitor of the TGFβ type I receptor Alk 5 - also inhibits Alk4&7). B: Soft agar assays were set up using MTLn3E cells that had been cultured in control media (+ vehicle) or with 2ng/ml TGFβ1 or 10μM SB431542 for 24 hours. Average of two experiments (error bars represent half range). C: MTLn3E tumour stained for pSmad3 (green) and DAPI (blue), tumour margin is in top right corner.

HHS Vulnerability Disclosure