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. 2009 Sep 10;18(23):4492–4500. doi: 10.1093/hmg/ddp408

Figure 4.

Figure 4.

X11β improves retention of water maze platform location in 12–16 months APPswe mice. Spatial memory retention in 12–16 months NTg, APPswe, X11β and APPswe/X11β mice were assessed in probe trials that determined the % of time spent in target quadrant (A), mean number of times the platform location was crossed (B) and latency to first reach the platform location (C). APPswe mice performed less well compared with all other genotypes and this effect was rescued in APPswe/X11β mice [one-way ANOVA with LSD post hoc test; P = 0.029 (A); P = 0.026 (B); P = 0.009 (C) n = 17–21]. * Indicate significant differences. Error bars are ± SEM.