Table 1.
Baseline Patient Characteristics With Both Baseline and 12-Month HRCT Scan Readings by Treatment Assignment
| Characteristics | CYC Group(n = 49) | Placebo Group(n = 49) | p Value* |
|---|---|---|---|
| Age, yr | 46.1 | 47.0 | 0.70 |
| Female gender | 38 (87.6) | 35 (71.4) | 0.49 |
| Disease duration, yr | 3.2 | 3.2 | 0.92 |
| FVC, % predicted | 68.3 | 69.8 | 0.52 |
| FEV1/FVC ratio | 82.3 | 82.9 | 0.74 |
| TLC, % predicted | 70.0 | 70.0 | 0.91 |
| FRC, % predicted | 76.0 | 71.9 | 0.29 |
| Dlco, % predicted | 46.0 | 47.9 | 0.50 |
| BDI (0–12) | 5.9 | 5.5 | 0.22 |
| Cough | 32 (68.1) | 36 (73.5) | 0.56 |
| SF-36 (0–100) | |||
| Physical component summary | 32.9 | 34.6 | 0.45 |
| Mental component summary | 48.5 | 50.8 | 0.29 |
| HAQ-DI (1–3) | 0.95 | 0.73 | 0.11 |
| Skin score (0–51) | 15.5 | 14.2 | 0.58 |
| HRCT scan score (range) | |||
| FIB | 2.0 (0–4) | 1.96 (0–4) | 0.89 |
| GGO | 0.67 (0–3) | 0.65 (0–2) | 0.61 |
| HC | 0.35 (0–3) | 0.41 (0–2) | 0.61 |
Values are given as the mean or No. (%), unless otherwise specified. BDI = baseline dyspnea index; FRC = functional residual capacity.
*Unpaired ttest.