Table 2.
Population | CD45RA | CD62L | Elimination rate, d−1*
|
|
---|---|---|---|---|
Normal | SIV | |||
CD4+ | ||||
+ | + | 0.007 ± 0.003 | 0.061 ± 0.047† | |
+ | − | 0.016 ± 0.003 | 0.055 ± 0.030† | |
− | + | 0.016 ± 0.005 | 0.112 ± 0.090† | |
− | − | 0.024 ± 0.004 | 0.107 ± 0.054† | |
CD8+ | + | + | 0.007 ± 0.003 | 0.054 ± 0.037† |
+ | + | 0.007 ± 0.003 | 0.054 ± 0.037† | |
+ | − | 0.007 ± 0.002 | 0.042 ± 0.027† | |
− | + | 0.032 ± 0.008 | 0.118 ± 0.076‡ | |
− | − | 0.028 ± 0.013 | 0.088 ± 0.053‡ |
Elimination rates for naive and memory T cells were calculated using nonlinear regression analysis of the washout phase in normal and SIV-infected macaques. Data are presented as the mean ± SD for normal and SIV-infected animals.
Significantly different than in normal animals, P < 0.01 (Mann–Whitney U test).
P < 0.05 (Mann–Whitney U test).