Table 1. Axonal transport flux and velocity of mitochondria and synaptic vesicle precursors in 3rd instar Drosophila larvae.
Axonal Transport of Mitochondria | |||||
FLUX (mitochondria/min) | control | pol γ-β1/Cyo | tam 3/Cyo | pol γ-β1/β2 | tam 3/tam 9 |
Anterograde | 10.15±2.48 | 10.17±2.33 | 13.66±2.56 | 16.31±5.47 | 18.20±4.87 |
Retrograde | 9.52±2.73 | 10.56±2.10 | 13.00±2.40 | 16.18±5.79 | 17.38±4.49 |
VELOCITY (µm/s) | control | pol γ-β1/Cyo | tam 3/Cyo | pol γ-β1/β2 | tam 3/tam 9 |
Anterograde | 0.08±0.01 | 0.06±0.01 | 0.07±0.01 | 0.05±0.01 | 0.05±0.01 |
Retrograde | 0.07±0.01 | 0.07+0.01 | 0.07+0.01 | 0.07+0.01 | 0.07+0.01 |
Axonal Transport of Synaptic Vesicle Precursors | |||||
FLUX (syn. vesicles/min) | control | pol γ-β1/β2 | tam 3/tam 9 | ||
Anterograde | 39.07±6.36 | 37.81±6.25 | 34.59±4.53 | ||
Retrograde | 35.46±5.45 | 32.87±6.10 | 30.48±6.32 | ||
VELOCITY (µm/s) | control | pol γ-β1/β2 | tam 3/tam 9 | ||
Anterograde | 0.08±0.02 | 0.08±0.02 | 0.08±0.01 | ||
Retrograde | 0.06±0.01 | 0.06+0.01 | 0.06+0.01 |
Axonal transport of mitochondria and synaptic vesicle precursors.
Flux and velocity values for bidirectional transport of mitochondria (UAS mtGFP) and synaptic vesicle precursors (UAS-n-sybGFP) in Drosophila larvae. Errors indicate standard deviation.