Table 1.
placebo | TMZ | RT | RT/TMZ | ||||||
---|---|---|---|---|---|---|---|---|---|
GBM# |
Rx day |
n |
survival, days |
n |
survival, days |
n |
survival, days |
n |
survival, days |
GBM5 | 22 | 8 | 55 | 10 | 321 | 10 | 139 | 9 | 349 |
GBM6 | 37 | 8 | 41 | 6 | 57 | 7 | 42 | 4 | 98 |
GBM8 | 44 | 8 | 58.5 | 8 | 123.5 | 8 | 107 | 8 | 189 |
GBM10 | 36 | 7 | 41 | 7 | 55 | 9 | 66 | 6 | 76 |
GBM12 | 11 | 10 | 15 | 10 | 53 | 10 | 37 | 10 | 85.5 |
GBM14 | 24 | 10 | 33 | 10 | 186 | 10 | 55.5 | 9 | 188 |
GBM15 | 29 | 10 | 54 | 10 | 252.5 | 9 | 250 | 10 | 252 |
GBM16 | 23 | 8 | 47.5 | 8 | 325.5 | 8 | 64 | 8 | 343 |
GBM22 | 38 | 8 | 43 | 8 | 154.5 | 8 | 43 | 8 | 325.5 |
GBM26 | 65 | 8 | 82.5 | 8 | 99.5 | 7 | 130 | 7 | 130 |
GBM28 | 30 | 8 | 33 | 7 | 56 | 7 | 68 | 8 | 82.5 |
GBM34 | 46 | 8 | 85 | 8 | 366.5 | 8 | 156 | 7 | 391 |
GBM36 | 44 | 8 | 125.5 | 8 | 228.5 | 8 | 194.5 | 8 | 307 |
GBM38 | 45 | 9 | 55 | 10 | 80 | 9 | 57 | 9 | 75 |
GBM39 | 28 | 10 | 31 | 10 | 120 | 10 | 50.5 | 10 | 202 |
GBM43 | 22 | 5 | 24 | 8 | 43 | 7 | 41 | 5 | 55 |
GBM44 | 31 | 9 | 35 | 7 | 59 | 9 | 104 | 10 | 113 |
GBM46 | 30 | 10 | 45 | 10 | 51 | 9 | 104 | 10 | 114.5 |
GBM58 | 51 | 10 | 91.5 | 10 | 102 | 9 | 100 | 10 | 111 |
GBM59 | 39 | 9 | 46 | 9 | 90 | 9 | 74 | 10 | 254 |
Rx day - number of days following tumor implantation that the 5-day therapy course was completed.
n - number of animals in each treatment group.
Survival - indicates the median survival in days for the indicated treatment.