Table 2.

Survival benefit following TMZ, RT or TMZ/RT

		Survival Ratio (p-value)
GBM#	MS-PCR	TMZ	RT	TMZ/RT
GBM5	M	5.84 (<0.0001)	2.53 (0.0003)	6.35 (<0.0001)
GBM6	U	1.39 (0.0005)	1.02 (0.23)	2.39 (0.04)
GBM8	M	2.11 (<0.0001)	1.83 (0.001)	3.23 (0.07)
GBM10	U	1.34 (0.10)	1.61 (0.003)	1.85 (0.0003)
GBM12	M	3.53 (<0.0001)	2.47 (<0.0001)	5.70 (<0.0001)
GBM14	M	5.64 (<0.0001)	1.68 (<0.0001)	5.70 (0.0003)
GBM15	M	4.68 (0.0001)	4.63 (<0.0001)	4.67 (0.0001)
GBM16	M	6.85 (0.02)	1.35 (0.47)	7.22 (0.10)
GBM22	M	3.59 (0.0009)	1.00 (0.29)	7.57 (0.0009)
GBM26	U	1.21 (0.003)	1.58 (0.0001)	1.58 (0.0001)
GBM28	U	1.70 (0.003)	2.06 (0.0001)	2.50 (<0.0001)
GBM34	U	4.31 (<0.0001)	1.84 (0.01)	4.60 (0.0001)
GBM36	M	1.82 (0.14)	1.55 (0.05)	2.45 (0.02)
GBM38	U	1.45 (0.0001)	1.04 (0.21)	1.36 (0.003)
GBM39	M	3.87 (<0.0001)	1.63 (<0.0001)	6.52 (<0.0001)
GBM43	U	1.79 (0.003)	1.71 (0.04)	2.29 (0.002)
GBM44	U	1.69 (0.05)	2.97 (0.008)	3.23 (<0.0001)
GBM46	M	1.13 (0.22)	2.31 (0.0007)	2.54 (<0.0001)
GBM58	U	1.11 (0.25)	1.09 (0.35)	1.21 (0.14)
GBM59	M	1.96 (<0.0001)	1.61 (0.0004)	5.52 (<0.0001)

MS-PCR - methylation specific PCR; M - methylated, U - unmethylated Survival ratio is the ratio of median survival for treatment vs. placebo.

p-value refers to the comparison of survival for the indicated treatment relative to placebo treatment.