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. 2009 Aug 3;114(18):3783–3792. doi: 10.1182/blood-2009-06-227843

Figure 2.

Figure 2

Growth kinetics of normal hematopoietic cells in leukemia-bearing mice. The percentages of normal hematopoietic cells (CD45.1+) in the leukemia group were monitored in both PB (A) and BM (B) 2 and 4 weeks after transplantation. In addition, the frequencies of GFP−CD45.2−CD45.1+Lin− and GFP−CD45.2−CD45.1+ LKS cells in BM were measured 1, 2, and 3 weeks after transplantation (C-D). P < .05 (n = 5/each, t test). Frequencies and absolute numbers of different hematopoietic cell populations within GFP−CD45.2−CD45.1+ BMNCs 4 weeks after transplantation are shown in the graphs (E-F). *P < .05 (t test). **P < .01 (t test). The BM cellularity of tibia, femur, iliac, and humerus was calculated as 40% of the total BM cellularity of a young adult C57BL/6J mouse (based on our own data). The data shown here represent 1 of 4 independent experiments (n = 6 or 7/group). Values are mean ± SD.