Table 2.
Summary of pathomorphological changes in the livers of C57BL/6J and mice fed a methyl-deficient diet for 18 weeks (mean ± S.D., n=5).
| Morphology | Histopathology score | |
|---|---|---|
| DBA/2J | C57BL/6J | |
| Steatosis | 4.8 ± 0.4* | 3.8 ± 0.8 |
| Necrosis | 3.8 ± 0.4* | 2.0 ± 0.7 |
| Inflammation | 2.0 ± 0.1 | 2.4 ± 0.9 |
| Oval cell hyperplasia | 2.6 ± 0.5* | 1.4 ± 0.5 |
| Karyocytomegaly | 2.4 ± 0.6* | 1.0 ± 0.1 |
Significantly different from C57BL/6J mice fed a MDD.