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. 2009 Sep;104(9):1549–1557. doi: 10.1111/j.1360-0443.2009.02653.x

Table 2.

Signs and symptoms related to opioid withdrawal and psychological distress.

SROM Mean± SD (median)
Methadone Mean± SD (mMedian)
Day 0 (n= 102) Day 22 (n= 52) P Day 0 (n= 99) Day 22 (n= 50) P
SOWS 8.07 ± 6.09 (7.00) 18.32 ± 8.98 (18.00) <0.001 8.15 ± 6.48 (7.00) 16.00 ± 7.81 (15.00) <0.001
SCL-90-R: Global Severity Index (GSI) 0.70 ± 0.56 (0.6) 0.74 ± 0.56 (0.58) 0.326 0.77 ± 0.58 (0.61) 0.67 ± 0.51 (0.52) 0.511

SCL: Symptom Checklist; SROM: slow-release oral morphine; SOWS: Short Opioid Withdrawal Scale; SD: standard deviation.