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. Author manuscript; available in PMC: 2010 Oct 20.
Published in final edited form as: Neuroscience. 2009 Jul 18;163(3):868–876. doi: 10.1016/j.neuroscience.2009.07.025

Figure 4.

Figure 4

Latency to find the hidden platform in the Morris water maze task. Animals that were pre-exposed to the binge EtOH regimen (ending 24 hr prior to Acquisition Day 1) and received intra-CA1 region Tat injection had significantly greater latencies to find the platform than all other groups, most notably, on training days 3 and 4. *= P <0.05 vs all other groups. This learning impairment was prevented by pre-treatment with the non-competitive NMDA receptor antagonist MK-801 (0.075mg/kg, i.p.).