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. 2009 Oct;1(4):a000034. doi: 10.1101/cshperspect.a000034

Figure 2.

Figure 2.

Members of the NF-κB, IκB, and IKK protein families. The Rel homology domain (RHD) is characteristic for the NF-κB proteins, whereas IκB proteins contain ankyrin repeats (ANK) typical for this protein family. The precursor proteins p100 and p105 can therefore be assigned to and fulfill the functions of both the NF-κB and IκB protein families. The domains that typify each protein are indicated schematically. CC, coiled-coil; DD, death domain; GRR, glycine-rich region; HLH, helix-loop-helix; IKK, IκB kinase; LZ, leucine-zipper; NBD, NEMO binding domain; PEST, proline-, glutamic acid-, serine-, and threonine-rich region; TAD, transactivation domain; ZF, zinc finger.