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Effect of H1152 (15 μg) on monkey IOP. H1152 or vehicle was administered topically on assigned eyes at 0 h. Assessment of IOP was conducted by a researcher who was unaware of the treatments at 0 h immediately before dosing and at 2 h, 4 h, and 6 h post-treatment. Error bars represent SEM of IOP values (n=6). The double asterisk indicates p<0.01 and three asterisks denote p<0.001 between the two groups by paired Student’s t-test.
