Figure 1. Immunostaining of FAK and p53 expression in breast cancer tumor with p53 mutation.

Example of high FAK and p53 staining in breast cancer tumor in patients positive for p53 mutation. Immunostaining of FAK and p53 was performed on different sections of tumors as described in Materials and Methods. FAK 4.47 antibody was used at dilution 1:250; p53 antibody was used (1:500). High FAK expression and p53 are shown. P53 was overexpressed in tumor with p53 mutation.