Table 2.

Correlation between FAK and p53 expression in breast cancer tumors.

FAK expression		p53 expression
	p53 positive (p53+)	p53 negative (p53−)
	N = 292	N = 330
	N (%)	N (%)
High FAK	91 (31%)	60 (18%)
Low FAK	201 (69%)	270 (82%)
OR = 2.0 (95% CI, 1.4–3.0)   unadjusted
OR = 1.8 (95% CI, 1.2–2.8)   adjusted for age, race and stage
P b =0.0002

	FAK intensity b	Mean	Median
p53 expression positive (p53+)	2.5	2.0	0–4
p53 expression negative (p53−)	1.9	2.0	0–4
Pc<0.0001

	FAK staining
	% positive c	Mean	Median
p53-positive	71.8%	80	0–99
p53-negative	62.9%	80	0–99
Pc=0.0005

^bChi-square test

^cStudent’s t-test